In the 2006 film *Casino Royale*, which serves as a "reboot" of the James Bond franchise, most of the main characters are meeting for the first time. Because this film depicts Bond’s first mission as a "00" agent, the narrative focuses on the formation of these iconic relationships.
Here is where the main characters know each other from:
### **1. James Bond and M (The Professional Relationship)**
* **Where they know each other from:** **MI6 Headquarters (London).**
* **Specific Detail:** As the head of MI6, M is Bond’s superior. While they have a pre-existing professional relationship, it is strained. At the start of the film, M has just promoted Bond to "00" status (giving him his license to kill) after he completes two assassinations in Prague. However, M privately admits she feels she promoted him "too soon" because of his reckless behavior in Madagascar.
* **Key Detail:** Bond does not know M’s personal details or even her real name at the start. He has to break into her home and use her computer to find out where she lives, telling her he found her address the "same way I found out your name"—suggesting he did a deep dive into classified MI6 files to learn more about her.
### **2. James Bond and Vesper Lynd (The Assigned Partnership)**
* **Where they know each other from:** **A high-speed train to Montenegro.**
* **Specific Detail:** They meet for the first time in the train's dining car. Vesper is a representative of **HM Treasury** (the Financial Action Task Force). She has been assigned by the British government to oversee the $10 million buy-in (and $5 million contingency) for the poker tournament.
* **Key Detail:** Their introduction is a famous "sizing up" scene where they trade sharp psychological deductions about one another. Vesper correctly identifies Bond as an orphan with a "chip on his shoulder," while Bond deduces that she is "prickly" because she feels the need to overcompensate in a male-dominated field.
### **3. James Bond and Le Chiffre (The Antagonist Relationship)**
* **Where they know each other from:** **The Casino Royale (Montenegro).**
* **Specific Detail:** Although Bond spends the first half of the movie thwarting Le Chiffre’s plans (specifically the bombing of the Skyfleet airliner in Miami), they do not meet face-to-face until the **poker tournament**.
* **Key Detail:** Bond knows *of* Le Chiffre through MI6 intelligence as a "private banker to the world's terrorists." Their relationship is purely adversarial, defined by the psychological warfare of the poker table.
### **4. James Bond and René Mathis (The Local Contact)**
* **Where they know each other from:** **The Hotel Splendide (Montenegro).**
* **Specific Detail:** Mathis is Bond’s **local MI6 contact** stationed in Montenegro. He meets Bond and Vesper upon their arrival at the hotel to provide them with local intelligence and support for the mission.
* **Key Detail:** Unlike the original Ian Fleming novel (where Bond and Mathis have a long history), the 2006 film presents them as meeting for the first time during this mission. Mathis assists Bond by helping frame the local police chief to ensure Bond’s cover remains intact.
### **5. James Bond and Felix Leiter (The CIA Alliance)**
* **Where they know each other from:** **The Poker Table / Stairwell at Casino Royale.**
* **Specific Detail:** They are fellow players in the high-stakes Texas Hold 'em tournament. They officially introduce themselves in a quiet moment on a staircase after Bond loses his initial $10 million buy-in and is about to assassinate Le Chiffre in desperation.
* **Key Detail:** Leiter reveals himself as a **CIA operative** and offers to "stake" Bond (give him the money to buy back into the game) using American funds. In exchange, Leiter demands that the CIA, rather than MI6, take custody of Le Chiffre after the game.
### **6. James Bond and Solange Dimitrios**
* **Where they know each other from:** **The Ocean Club (The Bahamas).**
* **Specific Detail:** Bond meets Solange at a beach club after tracking her husband, Alex Dimitrios, who is a middleman for Le Chiffre.
* **Key Detail:** Bond essentially seduces her to get information about her husband's whereabouts. This encounter is what leads Bond to Miami, where he prevents the Skyfleet explosion and indirectly forces Le Chiffre into the desperate poker game.